Citations found in two historical articles, which appeared in Cancer Research, a top Scientific Journal, were used to show both positive and negative attitudes towards my 21 historical publications written from 1958 to 2005 on cancer metastasis. Furthermore, scientific information concepts are cited critically so as to facilitate the derivation of a hypothesis which should promote the research of Third World scientists.

Non rotation of the gut is a rare pathological condition that frequently remains asymptomatic in adults and is only identified on incidental imaging. It may result in the delay of diagnosis of several common conditions; due to an atypical presentation. It tends to be identified in the paediatric population, because it is diagnosed secondary to an intestinal obstruction or volvulus. Here we present the case of a 49 year old patient who presented to the Emergency room with left lower quadrant tenderness. Initially, thought to be diverticulitis, however, a diagnostic CT scan of our patient revealed malrotation of the gut with the caecum in the left iliac fossa and duodeno -jejunal flexure and small bowel loops predominantly on the right. It revealed a dilated appendix with a distended lumen in the left mid lower quadrant of the abdomen with associated fat stranding. We proceeded with a laparoscopic appendectomy and a decision to not reverse the non-rotation of the gut. The purpose of this case report is to highlight an uncommon presentation of a common condition and to prevent delayed diagnosis.

Tuberculosis is one of the so-called social diseases; therefore the epidemiological parameters of tuberculosis are often used as an indicator of social well-being in the country [1]. At first glance, the existence of a link between suicide and tuberculosis mortality seems doubtful since suicidal behavior is a psychosocial phenomenon, while tuberculosis is an infectious disease. However, there are at least several possible aspects of such link at the individual level. First, there are arguments in favor of the psychosomatic nature of tuberculosis [2]. Here, the common etiological factor of suicidal behavior and tuberculosis can be psychosocial distress accompanied by a decrease in the immunity, in general, the body’s resistance, which increases the risk of tuberculosis [2]. Besides, an important aspect of existence of relationship between the suicidal behavior and tuberculosis is a suicidal behavior of patients with tuberculosis. One of the most common mental disorders in patients with tuberculosis is depression, which increases the risk of suicide [3]. The literature also reports of an increase in the risk of suicidal behavior against the background of anti-tuberculosis drugs [4].

Background: Right aortic arch is rare. It may be associated with critical subclavian stenosis. Case characteristics: A three month old baby presented with visible shortening of left arm. Observation: CT angiogram revealed right aortic arch with stenosis of left subclavian artery. Outcome: Gradual correction of limb discrepancy after successful Stenting. Message: Vaso-occlusive features may be a rare presentation of aortic arch anomalies.

The internists should utilize both their clinic experience and medical literature’s evidences, mediating with organizational context, patients’ opinion and ethics. However, none of these components may be sufficient. In several medical sectors, we may find many and extensive grey zones in which a diagnostic intervention’s effectiveness and/or its alternatives are uncertain. This cannot lead to the decision-making process’s paralysis, because the evidencebased medicine requires to base any clinical decision on “the best available evidences” and not on “the best possible evidences.” Clinicians should be able to extrapolate the prevailing question structuring from patients’ problem (PICO: problem, intervention, confront, outcome); identify the best available evidence and synthesize it; perform critical evaluation and information transfer (critical appraisal); in clinical efficiency, evaluate any action options.